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Septerna Inc (SEPN) Stock Forecast

Data as of Oct 31, 2026

Healthcare · Current price $43.80 (-3.16%)

Consensus Target
$50.40
Upside
+15.1%
Analysts
10
Rating
Buy(1.90)

Price Target Range

Low $43.00Consensus $50.40High $60.00
▲ Current $43.80

Consensus Price Target Over Time

Analyst Rating Distribution

Last 3 Months

Consensus
Buy
Strong Buy0
Buy5
Hold0
Sell0
Strong Sell0

6-Month Trend

Latest Analyst Forecasts

Price targets issued by Wall Street analysts. Upside calculated against today's price.

DateAnalystFirmPrice TargetUpside
Mar 10, 2026Josh SchimmerCantor Fitzgerald$60.00+37.0%
Dec 19, 2025Martin AusterRaymond James$38.00-13.2%
Nov 14, 2025Derek ArchilaWells Fargo$28.00-36.1%
May 16, 2025Derek ArchilaWells Fargo$18.00-58.9%
Feb 18, 2025Derek ArchilaWells Fargo$14.00-68.0%

SEPN vs Sector & Market

MetricSEPNHealthcare AvgLarge Cap Avg
Analyst Rating1.902.252.41
Analyst Count10819
Target Upside+15.1%+153002.0%+21.5%
P/E Ratio-21.993.4938.49

Revenue Estimates

PeriodLowAvgHigh#
2026-12-31$15M$22M$32M2
2027-03-31$7M$10M$14M2
2027-06-30$7M$10M$14M2
2027-09-30$7M$10M$14M2
2027-12-31$7M$10M$14M2
2028-12-31$42M$64M$87M6
2029-12-31$33M$50M$68M5
2030-12-31$57M$86M$118M3

EPS Estimates

PeriodLowAvgHigh#
2026-12-31$-0.74$-0.47$-0.282
2027-03-31$-1.17$-0.75$-0.452
2027-06-30$-1.08$-0.69$-0.421
2027-09-30$-1.27$-0.81$-0.491
2027-12-31$-1.38$-0.88$-0.532
2028-12-31$-3.51$-2.61$-1.695
2029-12-31$-5.12$-3.47$-1.921
2030-12-31$-5.59$-3.79$-2.101

Frequently Asked Questions

What is the analyst consensus for SEPN?

The consensus among 10 analysts covering Septerna Inc (SEPN) is Buy with an average price target of $50.40.

What is the highest price target for SEPN?

The highest price target for SEPN is $60.00, set by Josh Schimmer at Cantor Fitzgerald on 2026-03-10.

What is the lowest price target for SEPN?

The lowest price target for SEPN is $14.00, set by Derek Archila at Wells Fargo on 2025-02-18.

How many analysts cover SEPN?

10 analysts have issued ratings for Septerna Inc in the past 12 months.

Is SEPN a buy or sell right now?

Based on 10 analyst ratings, SEPN has a consensus rating of Buy (1.90/5) with a +15.1% upside to the consensus target of $50.40.

What are the earnings estimates for SEPN?

Analysts estimate SEPN will report EPS of $-0.47 for the period ending 2026-12-31, with revenue estimated at $22M.

Data updated daily. Analyst price targets sourced from public filings and broker reports. Not investment advice.