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Karyopharm Therapeutics Inc. (KPTI) Stock Forecast

Data as of May 2, 2026

Healthcare · Current price $8.77 (+5.48%)

Consensus Target
$14.17
Upside
+113.9%
Analysts
5
Rating
Buy(2.00)

Price Target Range

Low $6.00Consensus $14.17High $21.00
▲ Current $8.77

Consensus Price Target Over Time

Analyst Rating Distribution

Last 3 Months

Consensus
Buy
Strong Buy0
Buy4
Hold0
Sell0
Strong Sell0

6-Month Trend

Latest Analyst Forecasts

Price targets issued by Wall Street analysts. Upside calculated against today's price.

DateAnalystFirmPrice TargetUpside
Nov 4, 2025Brian AbrahamsRBC Capital$19.00+116.8%
Oct 13, 2025Robert BurnsH.C. Wainwright$15.00+71.1%
Jun 10, 2024Brian AbrahamsRBC Capital$3.00-65.8%
Aug 23, 2022Collen KusyRobert W. Baird$14.00+59.7%
Mar 10, 2022Brian AbrahamsRBC Capital$8.00-8.7%

KPTI vs Sector & Market

MetricKPTIHealthcare AvgLarge Cap Avg
Analyst Rating2.002.242.41
Analyst Count5818
Target Upside+113.9%+1150.1%+14.9%
P/E Ratio-0.796.8731.19

Revenue Estimates

PeriodLowAvgHigh#
2026-12-31$128M$137M$155M5
2027-12-31$145M$163M$181M4
2028-12-31$215M$215M$215M4
2029-12-31$318M$352M$401M3
2030-12-31$455M$505M$575M3

EPS Estimates

PeriodLowAvgHigh#
2026-12-31$-5.91$-4.37$-3.014
2027-12-31$-5.32$-3.18$-1.043
2028-12-31$-2.17$-1.17$-0.333
2029-12-31$3.05$3.50$4.131
2030-12-31$5.86$6.73$7.931

Frequently Asked Questions

What is the analyst consensus for KPTI?

The consensus among 5 analysts covering Karyopharm Therapeutics Inc. (KPTI) is Buy with an average price target of $14.17.

What is the highest price target for KPTI?

The highest price target for KPTI is $19.00, set by Brian Abrahams at RBC Capital on 2025-11-04.

What is the lowest price target for KPTI?

The lowest price target for KPTI is $3.00, set by Brian Abrahams at RBC Capital on 2024-06-10.

How many analysts cover KPTI?

5 analysts have issued ratings for Karyopharm Therapeutics Inc. in the past 12 months.

Is KPTI a buy or sell right now?

Based on 5 analyst ratings, KPTI has a consensus rating of Buy (2.00/5) with a +113.9% upside to the consensus target of $14.17.

What are the earnings estimates for KPTI?

Analysts estimate KPTI will report EPS of $-4.37 for the period ending 2026-12-31, with revenue estimated at $137M.

Data updated daily. Analyst price targets sourced from public filings and broker reports. Not investment advice.